Free 4-MU glucuronide <0.1%
Substrate for alpha-L-iduronidase.
Fluorogenic substrate for the study of Hurler - Scheie Syndrome [MPS-I]. Blood, 1 March 2002, Vol. 99, No. 5, pp.1857-1859.
This enzyme substrate has been found to be very useful in the study of Hurler - Scheie Syndrome [MPS-1], but the quality of research material available from some sources has often been poor. Glycosynth has supplied a top quality product since 1995, which has been approved in application by our customers and credited in research papers.
Our product is the free acid, which offers a considerable weight for weight advantage over the CHA salt [ 4-Methylumbelliferyl alpha-L-iduronic acid cyclohexylammonium salt, CAS 66895-33-8 ] in terms of its application dose.
Retrovirally mediated correction of bone marrow-derived mesenchymal stem cells from patients with mucopolysaccharidosis type I.