| CAS : |
142439-99-4 |
| Synonyms : |
4-Methylumbelliferyl N-acetyl-β-D-glucosaminide-6-sulfate sodium salt; 4MU N-acetyl-beta-D-glucosaminide-6-sulfate sodium salt |
| Product Code : |
44009 |
| Chemical Formula : |
C18H20NNaO11S |
| Molecular Weight : |
481.40 |
| Solubility : |
Soluble in water at a concentration of 5% |
| MDL Number : |
MFCD00132972 |
| Description |
Fluorogenic substrate used for the detection of N-acetyl-beta-D-glucosaminidase activity (hexosaminidase A), producing a blue fluorescence following hydrolysis. The substrate can be used for the pre-natal diagnosis of Tay-Sachs disease. Free 4-methylumbelliferyl N-acetyl-β-D-glucosamine, product code 44007 (Non-sulfated product) < 0.1%. |
To prevent deterioration, the product should be stored in tightly closed containers in a freezer or cold room at -20 degrees centigrade.
Sensitive fluorogenic substrate for Hex A in Tay-Sachs disease: J. Bayleran et al., Clin. Chim. Acta, 143, 73 (1984); G.T.N. Besley et al., NATO ASI Ser., Ser. A,150, 247 (1988).
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