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44076

4-Methylumbelliferyl alpha-L-iduronide (free acid)

4-Methylumbelliferyl alpha-L-iduronide (free acid)
Pack Size
Pack Price
No. of packs
2mg
£100.00
5mg
£250.00
10mg
£500.00
CAS : 66966-09-4
Synonyms : 4-Methylumbelliferyl α-L-iduronide (free acid); 4-Methylumbelliferyl alfa-L-iduronide (free acid); 4MU alpha-L-iduronide (free acid); 4MU alfa-L-iduronide (free acid); 4-MU alpha-L-iduronide (free acid); 4-MU alfa-L-iduronide (free acid); 4MU iduronide; 4-MU iduronide; 4-Methylumbelliferyl alpha-L-idopyranosiduronic acid; 4-Methylumbelliferyl alfa-L-idopyranosiduronic acid
Product Code : 44076
Chemical Formula : C16H16O9
Molecular Weight : 352.3
Solubility : Soluble in dimethylformamide/water 1:1 v/v at a concentration of 0.5%
MDL Number : MFCD00135894
Description Fluorogenic substrate used for the detection of alpha-L-iduronidase activity, producing a blue fluorescence following hydrolysis. This enzyme substrate has been found to be very useful in the study of Hurler - Scheie Syndrome [MPS-1]. Our product is the free acid, which offers a considerable weight for weight advantage over the CHA salt [4-Methylumbelliferyl alpha-L-iduronic acid cyclohexylammonium salt, CAS 66895-33-8] in terms of its application dose.

To prevent deterioration, the product should be stored in tightly closed containers in a freezer or cold room at -20 degrees centigrade.

Fluorogenic substrate for the study of Hurler - Scheie Syndrome [MPS-I]. Blood, 1 March 2002, Vol. 99, No. 5, pp.1857-1859.

Retrovirally mediated correction of bone marrow-derived mesenchymal stem cells from patients with mucopolysaccharidosis type I.

H. Church et al Bone Marrow Transplantation 39 207-10 2007

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